ITIS | Pain & Inflammation Support

ITIS | Pain & Inflammation Support

$68.00
Sale price  $68.00 Regular price 
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ITIS | Pain & Inflammation Support

ITIS

Pain & Inflammation Support

Immunity & Inflammation Immunity & Inflammation
Named as a direct reference to inflammation support—providing targeted botanical relief for pain and inflammatory discomfort.

How This Formula Helps You Feel

Targeted botanical support for reducing discomfort, supporting recovery, and maintaining comfort during physical stress.

  • Reduces discomfort and pain
  • Supports healthy inflammatory response
  • Promotes faster recovery
$68.00
Sale price  $68.00 Regular price 
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Made in USA
Easy Returns
60-Day Warranty
How to Take

Take 2 capsules two to three times per day, with or without food, or as directed by your healthcare practitioner.

Ingredients
Boswellia Serrata Extract Std. to 65% Boswellic Acids
Boswellia serrata

Boswellia is a resin from the Indian frankincense tree, used for joint comfort and ease of movement, particularly through ongoing physical wear. Its boswellic acids work alongside curcumin to support a balanced inflammatory response. We use it in formulas designed for long-term resilience rather than fast, short-acting relief — recovery rather than rescue.

Bromelain
Ananas comosus

Bromelain is a proteolytic enzyme from pineapple stem, used to support the body’s response to physical strain and post-activity recovery. It contributes to tissue comfort and works at a different level than herbal anti-inflammatories, which makes it a useful complement. We use it where active people need help recovering, not just resting.

Celery Seed
Apium graveolens

Celery seed is one of the older botanicals in the materia medica for joint comfort and fluid balance — especially when stiffness and physical strain are part of the picture. We include it for the comfort and movement side of recovery formulas, supporting the body’s natural balance during periods of physical stress.

Tart Cherry 4:1 Extract
Prunus cerasus

Tart cherry is one of the most well-supported botanicals for muscle comfort and post-activity recovery — popular among athletes and active people for exactly that reason. The 4:1 extract concentrates the anthocyanin profile responsible for its effect. We use it where the formula needs to support recovery rather than just management of the next session.

Organic Devil’s Claw Root
Harpagophytum procumbens

Devil’s claw is a southern African root with a long history of use for joint and muscle comfort, especially when physical strain is ongoing rather than acute. It plays a direct role in musculoskeletal support and pairs well with the anti-inflammatory profile of curcumin and boswellia. We use it where the discomfort doesn’t simply pass on its own.

Chinese Skullcap Root Extract
Scutellaria baicalensis

Chinese Skullcap is one of the most-cited herbs in classical East Asian medicine for immune balance and inflammatory signaling. Its baicalein-rich roots are particularly suited to formulas designed for sustained microbial or immune-system load. We use it where the body needs steady modulation, not stimulation, across multiple stress pathways.

Cat’s Claw Bark
Uncaria tomentosa

Cat’s Claw is a vining bark from the Peruvian Amazon, traditionally used to support immune function and overall system resilience. It contributes to balanced inflammatory signaling and is well-suited to formulas designed for prolonged stress or higher-demand wellness protocols. We use it where the body needs sustained immune capacity rather than short-term defense.

Curcumin Extract Std. to 95% Curcuminoids
Curcuma longa

Curcumin is the compound that gives turmeric its color and most of its therapeutic reputation. Standardized to 95% curcuminoids, it works at the cellular level to support a healthy inflammatory response — particularly the pathways involved in joint, muscle, and gut comfort. We use it as a foundation ingredient in any serious recovery or comfort-focused formula.

Organic Feverfew Powder
Tanacetum parthenium

Feverfew has been used for generations in herbal formulas focused on comfort and steadiness during stress-related discomfort, particularly the kind that builds gradually. It contributes to overall calm and balance in the formula and works alongside the more direct inflammation-modulating ingredients. We use it where the calming side of recovery matters too.

Quercetin Dihydrate

Quercetin is a flavonoid found in onions, apples, and capers, used for immune balance, healthy inflammatory response, and antioxidant protection. It also supports the transport of certain nutrients into cells. We use it in formulas focused on day-to-day sensitivity and stress resilience — broad support against the everyday load that erodes comfort.

BioPerine® Black Pepper Extract
Piper nigrum

BioPerine® is a standardized black pepper extract included specifically to enhance the bioavailability of other ingredients — most notably curcumin, which is poorly absorbed on its own. It’s a small ingredient with an outsized job. We include it where absorption is the difference between a formula working and the active sitting unused.

Ginger Essential Oil
Zingiber officinale

Ginger essential oil concentrates the volatile compounds that give the root its warming, mobilizing character. In inflammation- and comfort-focused formulas, it contributes to circulation and supports how the body processes physical stress. We use the oil form when we want ginger’s signature action in a more concentrated, low-volume dose alongside other essential oils.

Copaiba Essential Oil
Copaifera species

Copaiba is a resin from the Amazon basin, used as an essential oil to support comfort and a balanced inflammatory response. It carries beta-caryophyllene at unusually high concentrations, which is the compound most associated with its action. We use it for tissue-level comfort and overall balance in recovery-focused formulas.

Roman Chamomile Essential Oil
Chamaemelum nobile

Roman Chamomile essential oil is best known for its calming effect on the nervous system — the steadying ingredient when stress is part of the discomfort picture. It contributes to the comfort-and-calm side of recovery formulas, working alongside the more direct anti-inflammatory botanicals. We use it where ease of mind matters alongside ease of body.

Deep Dive: The Science

Deep Dive: The Science Behind This Formula

ITIS is formulated to support healthy inflammatory response and tissue comfort using botanicals that influence multiple inflammatory pathways. Rather than suppressing inflammation completely, the formula helps maintain balanced inflammatory signaling for optimal healing and comfort.

Multi‑Pathway Inflammatory Support

Different botanicals in ITIS target various inflammatory pathways, including prostaglandin regulation, cytokine balance, and tissue‑level inflammatory signaling. This creates broader support than single‑mechanism approaches.

Tissue Comfort and Recovery

The formula includes botanicals traditionally used to support joint, muscle, and soft tissue comfort. These compounds help maintain mobility and reduce discomfort during physical stress or recovery periods.

Supporting Natural Healing Processes

Healthy inflammation is necessary for healing. ITIS helps maintain balanced inflammatory response—supporting repair while reducing excessive inflammation that contributes to prolonged discomfort.

Antioxidant and Protective Support

Many inflammatory conditions involve oxidative stress. ITIS includes botanicals with antioxidant properties that help protect tissues during inflammatory stress and support recovery processes.

Designed for Physical Resilience

ITIS fits naturally into routines focused on physical performance, recovery, and comfort. It provides targeted support without interfering with the body's natural healing mechanisms.

Why cGMP Compliance Matters

Why cGMP Compliance Matters

We don’t take shortcuts when it comes to your health. Every Return Healthy formula is made in the United States in cGMP-compliant facilities with trusted manufacturing partners who follow strict standards for cleanliness, ingredient handling, batch consistency, documentation, and quality control.

cGMP stands for Current Good Manufacturing Practices — the FDA’s framework for making sure supplements are produced with consistency and accountability. It’s not easy to maintain, and that’s why it matters.

When something becomes part of your daily health routine, it should be made with care, precision, and integrity from the first ingredient to the finished bottle.

Third-Party Tested for Purity & Safety

We verify our formulas through independent third-party testing so you can feel confident about what you’re putting into your body. Testing helps confirm purity, safety, and product quality, including screening for unwanted contaminants like heavy metals, harmful microbes, and other concerns that don’t belong in a daily health routine.

For us, third-party testing is about accountability. It’s one more way we make sure every product meets the standard we’d expect for ourselves and our families.

High-Potency Ingredients
Gluten-Free
Non-GMO
All-Natural
Vegan
Dairy-Free
Soy-Free
Zero Fillers
No Preservatives
Inflammation Response

Built for targeted botanical support for inflammation, comfort, and recovery resilience.

ITIS combines botanicals traditionally used to support healthy inflammatory pathways, tissue comfort, and the body's natural recovery processes. Fourteen anti-inflammatory compounds target multiple pathways simultaneously — prostaglandin regulation, cytokine balance, tissue-level signaling — helping maintain comfort, mobility, and steadier recovery. Built to balance inflammation rather than suppress it, useful for both acute periods of physical strain and ongoing inflammatory burden.

01 Day-to-day differences
  • Reduced day‑to‑day discomfort and pain
  • Better mobility and range of movement
  • Improved recovery after physical stress
  • Greater overall comfort during demanding periods
02 Who this is for
ITIS is designed for individuals dealing with physical discomfort, inflammation, or recovery challenges. It's well‑suited for those experiencing joint, muscle, or soft tissue discomfort, people recovering from physical strain, or anyone needing targeted support during periods of increased inflammatory stress.
03 What to expect
Many people notice improvements in comfort and reduced inflammation with consistent use, though results depend on the level of physical demand and individual response. ITIS works gradually to support natural inflammatory balance rather than masking symptoms, so benefits tend to build with regular use.
04 How it works
ITIS combines botanicals traditionally used to support healthy inflammatory pathways, tissue comfort, and recovery processes. The formula helps regulate inflammatory signaling while supporting the body's natural repair mechanisms. By addressing inflammation at multiple pathways, ITIS helps maintain comfort, mobility, and faster recovery during periods of physical stress or discomfort.
ITIS
What it supports

System-level benefits

Inflammation Response

Balancing inflammation, not suppressing it

Fourteen anti-inflammatory compounds target multiple inflammatory pathways — prostaglandin regulation, cytokine balance, tissue-level signaling — supporting the body's natural healing rather than masking the response.

  • Multi-pathway inflammatory support
  • Fourteen anti-inflammatory compounds
  • Maintains healthy inflammation for healing

Inside the Formula

Fourteen anti-inflammatory compounds. Comfort and mobility support.

Boswellia Serrata

Boswellia serrata

Boswellia is a resin from the Indian frankincense tree, used for joint comfort and ease of movement, particularly through ongoing physical wear. Its boswellic acids work alongside curcumin to support a balanced inflammatory response. We use it in formulas designed for long-term resilience rather than fast, short-acting relief — recovery rather than rescue.

Extract Std. to 65% Boswellic Acids

Bromelain

Ananas comosus

Bromelain is a proteolytic enzyme from pineapple stem, used to support the body’s response to physical strain and post-activity recovery. It contributes to tissue comfort and works at a different level than herbal anti-inflammatories, which makes it a useful complement. We use it where active people need help recovering, not just resting.

Celery Seed

Apium graveolens

Celery seed is one of the older botanicals in the materia medica for joint comfort and fluid balance — especially when stiffness and physical strain are part of the picture. We include it for the comfort and movement side of recovery formulas, supporting the body’s natural balance during periods of physical stress.

Tart Cherry

Prunus cerasus

Tart cherry is one of the most well-supported botanicals for muscle comfort and post-activity recovery — popular among athletes and active people for exactly that reason. The 4:1 extract concentrates the anthocyanin profile responsible for its effect. We use it where the formula needs to support recovery rather than just management of the next session.

4:1 Extract

Organic Devil’s Claw Root

Harpagophytum procumbens

Devil’s claw is a southern African root with a long history of use for joint and muscle comfort, especially when physical strain is ongoing rather than acute. It plays a direct role in musculoskeletal support and pairs well with the anti-inflammatory profile of curcumin and boswellia. We use it where the discomfort doesn’t simply pass on its own.

Chinese Skullcap Root Extract

Scutellaria baicalensis

Chinese Skullcap is one of the most-cited herbs in classical East Asian medicine for immune balance and inflammatory signaling. Its baicalein-rich roots are particularly suited to formulas designed for sustained microbial or immune-system load. We use it where the body needs steady modulation, not stimulation, across multiple stress pathways.

Cat’s Claw Bark

Uncaria tomentosa

Cat’s Claw is a vining bark from the Peruvian Amazon, traditionally used to support immune function and overall system resilience. It contributes to balanced inflammatory signaling and is well-suited to formulas designed for prolonged stress or higher-demand wellness protocols. We use it where the body needs sustained immune capacity rather than short-term defense.

Curcumin Extract

Curcuma longa

Curcumin is the compound that gives turmeric its color and most of its therapeutic reputation. Standardized to 95% curcuminoids, it works at the cellular level to support a healthy inflammatory response — particularly the pathways involved in joint, muscle, and gut comfort. We use it as a foundation ingredient in any serious recovery or comfort-focused formula.

Std. to 95% Curcuminoids

Organic Feverfew Powder

Tanacetum parthenium

Feverfew has been used for generations in herbal formulas focused on comfort and steadiness during stress-related discomfort, particularly the kind that builds gradually. It contributes to overall calm and balance in the formula and works alongside the more direct inflammation-modulating ingredients. We use it where the calming side of recovery matters too.

Quercetin Dihydrate

Quercetin is a flavonoid found in onions, apples, and capers, used for immune balance, healthy inflammatory response, and antioxidant protection. It also supports the transport of certain nutrients into cells. We use it in formulas focused on day-to-day sensitivity and stress resilience — broad support against the everyday load that erodes comfort.

BioPerine®

Piper nigrum

BioPerine® is a standardized black pepper extract included specifically to enhance the bioavailability of other ingredients — most notably curcumin, which is poorly absorbed on its own. It’s a small ingredient with an outsized job. We include it where absorption is the difference between a formula working and the active sitting unused.

Black Pepper Extract

Ginger

Zingiber officinale

Ginger essential oil concentrates the volatile compounds that give the root its warming, mobilizing character. In inflammation- and comfort-focused formulas, it contributes to circulation and supports how the body processes physical stress. We use the oil form when we want ginger’s signature action in a more concentrated, low-volume dose alongside other essential oils.

Essential Oil

Copaiba

Copaifera species

Copaiba is a resin from the Amazon basin, used as an essential oil to support comfort and a balanced inflammatory response. It carries beta-caryophyllene at unusually high concentrations, which is the compound most associated with its action. We use it for tissue-level comfort and overall balance in recovery-focused formulas.

Essential Oil

Roman Chamomile

Chamaemelum nobile

Roman Chamomile essential oil is best known for its calming effect on the nervous system — the steadying ingredient when stress is part of the discomfort picture. It contributes to the comfort-and-calm side of recovery formulas, working alongside the more direct anti-inflammatory botanicals. We use it where ease of mind matters alongside ease of body.

Essential Oil

What to Expect

Your recovery timeline

ITIS works systemically to support a balanced inflammatory response. Meaningful shifts tend to build over weeks of consistent use rather than hours.

Weeks 0-2

Your body is adjusting to anti-inflammatory support

Some people notice early shifts in comfort, stiffness, or recovery. Others feel very little at first, which is also normal. Start consistently and let the formula build.

Weeks 3-6

Comfort and mobility start to improve

More sustained physical comfort, less stiffness after rest, and easier recovery after activity. Curcumin and Boswellia tend to show more noticeable effects as they build up in this window.

Week 7+

A more resilient baseline for comfort

Many people describe a quieter, more stable baseline with fewer flares, better recovery, and an overall sense that their body handles physical demands more gracefully.

Individual results vary. ITIS is not intended to replace medical care for inflammatory conditions. Always consult your health care practitioner before starting or changing any supplement routine.

FAQs

About This Product

What is ITIS designed to support?

ITIS supports healthy inflammatory response, tissue comfort, and recovery processes during periods of physical stress or discomfort.

Does ITIS act like a pain reliever?

No. ITIS supports natural inflammatory pathways and recovery processes rather than masking pain symptoms like conventional pain relievers.

How is ITIS typically used?

ITIS is often used during periods of increased physical stress, recovery phases, or when ongoing inflammatory support is needed.

Can ITIS be combined with other supplements?

Yes. ITIS pairs well with foundational formulas, recovery support, and other wellness routines focused on physical resilience and comfort.

What makes ITIS different from other anti‑inflammatory supplements?

ITIS combines multiple botanicals that address different inflammatory pathways simultaneously, providing broader, more comprehensive support than single‑ingredient anti‑inflammatory formulas.

General FAQs

Can I return an opened product?

Yes — we understand that sometimes you need to try a product to know if it’s right for you.

Opened products may be eligible for store credit within 60 days of purchase. If a return label is provided, the cost may be deducted from the store credit.

How long does shipping take?

Most orders arrive within 3–6 business days, though delivery times are not guaranteed.

If you need it sooner, expedited shipping options like UPS 2nd Day Air® and UPS Next Day Air® are available at checkout.

How much does shipping cost?

We offer free standard shipping on orders over $80, so most customers qualify automatically.

For orders below that, or shipments to Hawaii and Alaska, we always select the most reliable and cost-effective shipping option available.

What is your return policy?

We stand behind every product we make. If something doesn’t feel right, let us know — we’ll work with you to make it right.

Unopened products can be returned within 60 days of purchase if they are in their original, sealed condition. Shipping charges are not refundable, and if a return label is provided, the cost may be deducted from your refund.

When will my order ship?

We ship quickly so you can get started right away.

Orders placed before 11:00 AM MT (Monday–Friday) typically ship the same business day. Orders placed after the cutoff, on weekends, or on holidays will ship the next business day.

Where are your products manufactured?

All of our products are manufactured in the United States in GMP-certified facilities.

We work with high-quality manufacturing partners to ensure consistency, purity, and standards you can trust with every batch.

FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Please consult your health care practitioner before starting any dietary supplement or herbal regimen.

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